The Macedonian king Alexander the Great descended from Epirus, form his mother Olympiad, the daughter of Neoptolemus 1st, king of Molossus. Molossus kingdom, a great epirotic tribe, reaches its maximum flourishing in the 3rd century B.C., during king Pyrrhus’s era. Pyrrhus managed to unify all epirotic tribes, and attempted to conquer the Italian Peninsula. Unified Epirus – Northern and Southern – from Acheloos River up to Aoos River, experienced a period of glory and grandeur. One century later, the Romans dominated, and a period of decline and disaster come for the Greek cultural inheritance in unified Epirus.